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1

Increased Protein Degradation Improves Influenza Virus Nucleoprotein-specific CD8 + T cell Activation in vitro but not in C57BL/6 mice

Altenburg, Arwen F, van de Sandt, Carolien E, van Trierum, Stella E, De Gruyter, Heidi L. M., van Run, Peter R. W. A., Fouchier, Ron A. M., Roose, Kenny, Saelens, Xavier, Volz, Asisa, Sutter, Gerd, de

Journal:

Journal of Virology

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

2

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

Van Hoecke, Lien, Van Lint, Sandra, Roose, Kenny, Van Parys, Alexander, Vandenabeele, Peter, Grooten, Johan, Tavernier, Jan, De Koker, Stefaan, Saelens, Xavier

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 3.22 MB

english, 2018

3

Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization

Leemans, Annelies, Boeren, Marlies, Van der Gucht, Winke, Pintelon, Isabel, Roose, Kenny, Schepens, Bert, Saelens, Xavier, Bailey, Dalan, Martinet, Wim, Caljon, Guy, Maes, Louis, Cos, Paul, Delputte,

Journal:

Year:

2018

Language:

english

File:

PDF, 3.89 MB

english, 2018

4

mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Van Hoecke, Lien, Verbeke, Rein, De Vlieger, Dorien, Dewitte, Heleen, Roose, Kenny, Van Nevel, Sharon, Krysko, Olga, Bachert, Claus, Schepens, Bert, Lentacker, Ine, Saelens, Xavier

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 2.18 MB

2020

5

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

Wrapp, Daniel, De Vlieger, Dorien, Corbett, Kizzmekia S., Torres, Gretel M., Wang, Nianshuang, Van Breedam, Wander, Roose, Kenny, van Schie, Loes, Hoffmann, Markus, PÃ¶hlmann, Stefan, Graham, Barney S

Journal:

Year:

2020

File:

PDF, 6.03 MB

2020

6

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

Wrapp, Daniel, De Vlieger, Dorien, Corbett, Kizzmekia S., Torres, Gretel M., Wang, Nianshuang, Van Breedam, Wander, Roose, Kenny, van Schie, Loes, Hoffmann, Markus, PÃ¶hlmann, Stefan, Graham, Barney S

Journal:

Year:

2020

File:

PDF, 2.79 MB

2020

7

M2e-based universal influenza A vaccine

Walter Fiers, Marina De Filette, Karim El Bakkouri, Bert Schepens, Kenny Roose, Michael Schotsaert, Ashley Birkett, Xavier Saelens

Journal:

Year:

2009

Language:

english

File:

PDF, 115 KB

english, 2009

8

Hepatitis B core–based virus–like particles to present heterologous epitopes

Roose, Kenny, Baets, Sarah De, Schepens, Bert, Saelens, Xavier

Journal:

Expert Review of Vaccines

Year:

2013

Language:

english

File:

PDF, 1.95 MB

english, 2013

9

Influenza vaccines to control influenza-associated bacterial infection: where do we stand?

Christopoulou, Ioanna, Roose, Kenny, Ibañez, Lorena Itatí, Saelens, Xavier

Journal:

Expert Review of Vaccines

Year:

2015

Language:

english

File:

PDF, 541 KB

english, 2015

10

Sequence-dependent Internalization of Aggregating Peptides

Couceiro, José R., Gallardo, Rodrigo, De Smet, Frederik, De Baets, Greet, Baatsen, Pieter, Annaert, Wim, Roose, Kenny, Saelens, Xavier, Schymkowitz, Joost, Rousseau, Frederic

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 5.42 MB

english, 2015

11

Structure of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus in Complex with a Protective Monoclonal Antibody

Cho, Ki Joon, Schepens, Bert, Seok, Jong Hyeon, Kim, Sella, Roose, Kenny, Lee, Ji-Hye, Gallardo, Rodrigo, Van Hamme, Evelien, Schymkowitz, Joost, Rousseau, Frederic, Fiers, Walter, Saelens, Xavier, Ki

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

12

A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection

Maelfait, Jonathan, Roose, Kenny, Bogaert, Pieter, Sze, Mozes, Saelens, Xavier, Pasparakis, Manolis, Carpentier, Isabelle, van Loo, Geert, Beyaert, Rudi, Pekosz, Andrew

Journal:

Year:

2012

Language:

english

File:

PDF, 536 KB

english, 2012

13

Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses

De Beuckelaer, Ans, Pollard, Charlotte, Van Lint, Sandra, Roose, Kenny, Van Hoecke, Lien, Naessens, Thomas, Udhayakumar, Vimal Kumar, Smet, Muriel, Sanders, Niek, Lienenklaus, Stefan, Saelens, Xavier,

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

14

Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

Van den Hoecke, Silvie, Ehrhardt, Katrin, Kolpe, Annasaheb, El Bakkouri, Karim, Deng, Lei, Grootaert, Hendrik, Schoonooghe, Steve, Smet, Anouk, Bentahir, Mostafa, Roose, Kenny, Schotsaert, Michael, Sc

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

15

Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection

Pendzialek, Jochen, Roose, Kenny, Smet, Anouk, Schepens, Bert, Kufer, Peter, Raum, Tobias, Baeuerle, Patrick A., Muenz, Markus, Saelens, Xavier, Fiers, Walter

Journal:

Antiviral Research

Year:

2017

Language:

english

File:

PDF, 2.00 MB

english, 2017

16

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

Udhayakumar, Vimal K., De Beuckelaer, Ans, McCaffrey, Joanne, McCrudden, Cian M., Kirschman, Jonathan L., Vanover, Daryll, Van Hoecke, Lien, Roose, Kenny, Deswarte, Kim, De Geest, Bruno G., Lienenklau

Journal:

Advanced Healthcare Materials

Year:

2017

Language:

english

File:

PDF, 3.02 MB

english, 2017

17

Bronchoalveolar Lavage of Murine Lungs to Analyze Inflammatory Cell Infiltration

Van Hoecke, Lien, Job, Emma Richelle, Saelens, Xavier, Roose, Kenny

Journal:

Journal of Visualized Experiments

Year:

2017

Language:

english

File:

PDF, 360 KB

english, 2017

18

Oral delivery of Escherichia coli persistently infected with M2e-displaying bacteriophages partially protects against influenza A virus

Deng, Lei, Roose, Kenny, Job, Emma R., De Rycke, Riet, Van Hamme, Evelien, Goncalves, Amanda, Parthoens, Eef, Cicchelero, Laetitia, Sanders, Niek, Fiers, Walter, Saelens, Xavier

Journal:

Journal of Controlled Release

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

19

M2e-Displaying Virus-Like Particles with Associated RNA Promote T Helper 1 Type Adaptive Immunity against Influenza A

Ibañez, Lorena Itatí, Roose, Kenny, De Filette, Marina, Schotsaert, Michael, De Sloovere, Jessica, Roels, Stefan, Pollard, Charlotte, Schepens, Bert, Grooten, Johan, Fiers, Walter, Saelens, Xavier, Di

Journal:

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

20

A GFP Expressing Influenza A Virus to Report In Vivo Tropism and Protection by a Matrix Protein 2 Ectodomain-Specific Monoclonal Antibody

De Baets, Sarah, Verhelst, Judith, Van den Hoecke, Silvie, Smet, Anouk, Schotsaert, Michael, Job, Emma R., Roose, Kenny, Schepens, Bert, Fiers, Walter, Saelens, Xavier, Krammer, Florian

Journal:

Year:

2015

Language:

english

File:

PDF, 3.75 MB

english, 2015

21

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

Maelfait, Jonathan, Roose, Kenny, Vereecke, Lars, Mc Guire, Conor, Sze, Mozes, Schuijs, Martijn J., Willart, Monique, Itati Ibañez, Lorena, Hammad, Hamida, Lambrecht, Bart N., Beyaert, Rudi, Saelens,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.66 MB

english, 2016

22

Inﬂuenza and Memory T Cells: How to Awake the Force

Spitaels, Jan, Roose, Kenny, Saelens, Xavier

Journal:

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

23

How mRNA therapeutics are entering the monoclonal antibody field

Van Hoecke, Lien, Roose, Kenny

Journal:

Journal of Translational Medicine

Year:

2019

Language:

english

File:

PDF, 2.05 MB

english, 2019

24

Reverse engineering synthetic antiviral amyloids

Michiels, Emiel, Roose, Kenny, Gallardo, Rodrigo, Khodaparast, Ladan, Khodaparast, Laleh, van der Kant, Rob, Siemons, Maxime, Houben, Bert, Ramakers, Meine, Wilkinson, Hannah, Guerreiro, Patricia, Lou

Journal:

Nature Communications

Year:

2020

File:

PDF, 3.08 MB

2020

25

The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration

Van Hoecke, Lien, Roose, Kenny, Ballegeer, Marlies, Zhong, Zifu, Sanders, Niek N., De Koker, Stefaan, Saelens, Xavier, Van Lint, Sandra

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 1.53 MB

2020